U.S. Food & Drug Administration Direct download
FDA public data as JSON APIs and bulk downloads: drug adverse-event reports (FAERS), drug labels, recalls and enforcement actions, device adverse events, and NDC product listings.
Humanity’s most complete public ledger of what happened after we swallowed, injected, or implanted something.
- Formats
- JSON API · bulk JSON (zipped)
- Size
- ~GBs per endpoint (adverse events are the big one)
- License
- Public domain (CC0)
- Updated
- Regularly (endpoint-dependent)
Official site ↗ Bulk downloads ↗
U.S. National Library of Medicine Direct download
The current FDA label (Structured Product Labeling) for essentially every marketed drug in the U.S. — full prescribing information as structured XML, downloadable in bulk.
The fine print of every pill bottle in the country, machine-readable.
- Formats
- XML (SPL) · bulk ZIP releases · REST API
- Size
- ~145k+ labels; multi-GB in bulk
- License
- Public domain
- Updated
- Daily
Official site ↗ Bulk downloads ↗
U.S. Food & Drug Administration Direct download
Approved drug products with therapeutic-equivalence evaluations — the authoritative list behind generic substitution, plus patent and exclusivity data, as plain downloadable data files.
The book pharmacists argue with. Now a ZIP file.
- Formats
- TXT (delimited) in ZIP
- Size
- ~MBs
- License
- Public domain
- Updated
- Monthly
Official site ↗ Bulk downloads ↗
DrugBank (University of Alberta / OMx) Free registration required
The freely licensed subset of DrugBank: the open drug & drug-target vocabulary (identifiers, names, CAS/UNII mappings) released under CC0. The full database requires a license — this subset does not.
- Formats
- CSV (zipped)
- Size
- ~MBs
- License
- CC0 1.0 (open subset only)
- Updated
- With DrugBank releases
Official site ↗
U.S. National Library of Medicine Free registration required
The normalized naming system that lets U.S. drug databases talk to each other — every clinical drug, dose form, and brand mapped to stable identifiers. Full monthly releases downloadable with a free UMLS account.
The Rosetta Stone for why your pharmacy’s computer and your hospital’s computer disagree.
- Formats
- RRF (pipe-delimited) · API (JSON)
- Size
- ~100s of MBs
- License
- Free; UMLS Metathesaurus License (free account) for full files
- Updated
- Monthly
Official site ↗